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            Agilent Thought Leader Program

            This invitational program promotes fundamental scientific advancements by contributing financial support, products and expertise to the research of influential thought leaders in the life sciences, diagnostics, and chemical analysis.


            Publications

             

            Thought Leader Award Recipients

            Dr. Antoni Ribas

            Dr. Diether Lambrechts

            Dr. Paul Bonnington

            Dr. Kimbal Marriott

            Dr. Kristina Hakansson

            Dr. Brandon Ruotolo

            Dr. Jiandong Jiang

            Dr. Ram Sasisekharan

            Dr. Dwight R. Stoll

            Dr. Shane A. Snyder

            Dr. Rohit Bhargava

            Dr. Scott W. Lowe

            Dr. Peter Robinson

            Dr. Shilin Chen

            Dr. Jeffrey I. Gordon

            Dr. Lawrence J. Lesko

            Dr. Arturo A. Keller

            Dr. Jules Griffin

            Dr. Carlos Cordon-Cardo

            Dr. Carolyn Mountford

            Dr. John A. McLean

            Dr. Joshua D. Rabinowitz

            Dr. Paul B. Watkins

            Dr. Junying Yuan

            Dr. Guibin Jiang

            Dr. Emmanuel Barillot

            Dr. Hashim Al-Hashimi

            Dr. Ronald DePinho

            Dr. Robert Gerszten

            Dr. Jens Frisvad

            Dr. Russell Thomas

            Dr. Chris Evelo

            Dr. Steven Carr

            Dr. Gerhard Wagner

            Dr. Adam Arkin

            Dr. Bart Weimer

            Dr. David Botstein

            Dr. Hailu Kinde

            Dr. Thomas Hartung

            Dr. James Collins

            Dr. George Church

            Dr. Don Ingber

            Dr. Janne Lehtio

            Dr. Pauline Rudd

             


            Thought Leader Award Recipients:

            Dr. Antoni Ribas

            Dr. Antoni Ribas
            Professor of Medicine, Surgery, Molecular and Medical Pharmacology
            Director of the Tumor Immunology Program at the Jonsson Comprehensive Cancer Center
            Director of the Parker Institute for Cancer Immunotherapy Center
            University of California Los Angeles
            Los Angeles, CA

            Dr. Ribas is a melanoma expert and conducts laboratory and clinical research in malignant melanoma. His work focuses on elucidating the mechanism of action and improving the patient outcome from treatments based on gene engineered adoptive cell transfer (ACT) therapies, immunotherapy, small molecule inhibitors and siRNA therapeutics. His laboratory develops models of disease to test new therapeutic options and in patients. The aim of his work is to improve the molecular genetic annotation of cancer as well as to identify cancer cell susceptibilities, new targets for therapeutic and biomarkers for better stratification of patients for treatment. The Agilent Thought Leader award will support his genomics and epigenomics efforts to identify patient biomarkers involved in the resistance to current immunotherapeutic treatments. (press release)

            Dr. Diether Lambrechts

            Dr. Diether Lambrechts
            Professor of Human Genetics
            Catholic University of Leuven (KU Leuven)
            Director of The Laboratory of Translational Genetics  
            VIB-KU Leuven Center for Cancer Biology
            Belgium

            Dr. Lambrechts conducts translational cancer research using genomics and epigenomics approaches. The aim of his work is to improve the molecular genetic annotation of cancer as well as to identify cancer cell susceptibilities, new targets for therapeutic and biomarkers for better stratification of patients for treatment. The Agilent Thought Leader award will support his current efforts to apply single cell genomics analysis of cancer cells to identify the mechanism of resistance to cancer immunotherapy. For his influential work, Dr. Lambrechts has been recognized in the past by several awards, including the AstraZeneca Award for Translational Research. (press release)

            Dr. Paul Bonnington

            Dr. Paul Bonnington
            Director eResearch Centre
            Monash University
            Melbourne, Australia

            Awarded in February 2019

            Dr. Paul Bonnington serves on the steering committees for the Victorian Life Sciences Computing Initiative and National Computational Infrastructure's Specialist Facility for Imaging and Visualization. He served as the Chair of the Steering Committee for the Australian National Data Service Establishment Project. Paul's research interests lie in Combinatorial Computing, and Discrete and Computational Geometry. (press release)

            Dr. Kimbal Marriot

            Dr. Kimbal Marriott
            Professor in Computer Science
            Monash University
            Melbourne, Australia

            Awarded in February 2019

            Dr. Marriott leads the Computer Human Interaction and Creativity (CHIC) discipline group. He joined Monash in 1993 after working for five years at the IBM TJ Watson Research Center. His main current interests are in information visualization, immersive analytics, digital publishing as well as assistive technologies for people with vision impairment. (press release)

            Dr. Kristina Hakansson

            Dr. Kristina Hakansson
            Professor of Chemistry
            University of Michigan
            College of Literature, Science and the Arts
            University of Michigan
            Ann Arbor, MI

            Awarded in April 2018

            Dr. Hakansson has made numerous contributions to the development of mass spectrometry techniques for identification and analysis of modifications and structural characterization of biomolecules. She developed negative ion electron capture dissociation (niECD) and demonstrated the ability of this method to characterize phosphorylated and sulfated peptides. Additionally, she showed that electron-activated dissociation methods are gentle enough to allow preservation of higher order structures of nucleic acids.  Dr. Hakansson’s current research focuses on characterization of protein posttranslational modifications by complementary fragmentation techniques such as ECD and infrared multiphoton dissociation (IRMPD) at low (femtomole) levels. Dr. Hakansson has been recognized with a  number of prestigious awards including the National Science Foundation Career Award, the American Society for Mass Spectrometry Research Award, the Eli Lilly Analytical Chemistry Award and the Biemann Medal from the American Society for Mass Spectrometry, among others. (press release)

            Dr. Brandon Ruotolo

            Dr. Brandon Ruotolo
            Associate Professor of Chemistry
            College of Literature, Science and the Arts
            University of Michigan
            Ann Arbor, MI

            Awarded in April 2018

            Dr. Ruotolo’s work is focused on developing ion mobility-mass spectrometry (IM-MS) as a tool for structural biology and in particular developing gas-phase measurement strategies to resolve long-term challenges in high-throughput structural biology and drug discovery. This includes work on i) instrument development, ii) construction of computational tools for IM-MS data analysis and 3D model generation, and iii) development of collision induced unfolding (CIU) of protein complexes in the gas-phase. His long-term aim is to utilize IM-MS data alongside other protein structure determination approaches to support the emerging field of integrative structural biology – where many pieces of data derived from disparate techniques are combined to generate a more-complete picture of an assembly than was possible with any one tool. Dr Ruotolo has received many awards for his work, including the American Society for Mass Spectrometry Research Award, the National Science Foundation Career Award, Eli Lilly Young Investigator Award and the Protein Society Young Investigator Award. (press release)

            Professor Jiandong Jiang

            Dr. Jiandong Jiang
            Director of the Institute of Materia Medica,
            Chinese Academy of Medical Sciences
            & Peking Union Medical College

            Awarded in July 2017

            Professor Jiang has contributed to the adoption of genomics, metabolomics and integrated biology analysis to the study of traditional Chinese medicines. These efforts have facilitated the identification of their mechanisms of action as well as to the identification of the affected pathways, thus identifying new alternative targets for therapeutic intervention. Professor Jiang’s work extends from antimicrobial to cancer and metabolic diseases. (press release)

            Dr. Ram Sasisekharan

            Dr. Ram Sasisekharan
            Alfred H. Caspary Professor of Biological Engineering and Health Sciences & Technology
            Massachusetts Institute of technology
            Cambridge, MA

            Awarded in April 2017

            Dr. Sasisekharan has been a professor of biological engineering at MIT since 1996, and has served as the director of the Harvard-MIT Division of Health Sciences & Technology from 2008-2012. The Sasisekharan lab employs multidisciplinary strategies to develop and integrate orthogonal analytical technologies to further research into complex biopharmaceuticals. The lab originated its efforts with GAGs (such as heparin) to develop analytical and enzymatic tools with the pertinent and defined substrate-product profiles required to understand their structure-function relationships. Timely development and characterization of therapeutic mAb to treat infectious diseases and cancer are currently of paramount interest to his lab. Dr. Sasisekharan has been recognized by numerous accolades and awards, and his ideas and concepts have been the founding basis of many biotechnology companies. (press release)

            Dr. Dwight R. Stoll

            Dr. Dwight R. Stoll
            Associate Professor of Analytical Chemistry
            Co-chair of the Chemistry Department
            Gustavus Adolphus College
            Saint Peter, Minnesota

            Awarded in March 2017

            Dr. Stoll is widely recognized for his efforts and contributions to analytical chemistry and separation sciences. His active research projects include the development of rapid multidimensional liquid chromatography for targeted and untargeted analysis in complex matrices and optimization of isocratic and gradient elution HPLC. He has pioneered the development of 2D-HPLC and its applications in BioPharma.

            Dr. Stoll has received numerous awards and recognitions including the John B. Phillips Award for contributions to multidimensional gas chromatography, the LCGC’s Emerging Leader in Chromatography Award. In 2014 he was named to The Analytical Scientist’s list of ‘Top 40 Under 40’ analytical scientists and received the American Chemical Society Division of Analytical Chemistry Award for Young Investigators in Separation Science in 2015. In 2016 he received the Palmer Award from the Minnesota Chromatography Forum and the Gustavus Faculty Scholarly Achievement. Earlier this year he received the Eastern Analytical Symposium Young Investigator Award. (press release)

            Dr. Shane A. Snyder

            Dr. Shane A. Snyder
            Professor - Chemical and Environmental Engineering
            Co-Director of the Arizona Laboratory for Emerging Contaminants (ALEC) and the Water & Energy Sustainable Technology (WEST) Center
            University of Arizona
            Tucson, AZ

            Awarded in October 2016

            Dr. Snyder is widely recognized for his efforts and contributions to the analysis and management of water pollutants. His research focuses on the development and application of methodologies to identify and quantify known and unknown environmental contaminants using a wide-array of state of the art analytical instrumentation. Likewise, his work includes use of in vitro bioassays to analyze toxicological effects of water contaminants. Additionally, Dr. Snyder's engineering research focuses on the development of water treatment technologies that minimize energy consumption and maximize water quality.

            Dr. Snyder is Co-Editor in Chief of the international journal Chemosphere and was selected as fellow of the International Water Association in 2016 for his work combating water challenges worldwide. (press release)

            Dr. Rohit Bhargava

            Dr. Rohit Bhargava
            Founder Professor of Engineering and Chemistry | Director, Cancer Center at Illinois
            Depts. of Bioengineering, Electrical & Computer Sciences, Mechanical Science & Engineering, Chemical & Biomolecular Engineering and Chemistry
            University of Illinois at Urbana-Champaign
            Urbana, IL

            Awarded in October 2016

            Dr. Bhargava is widely recognized for his pioneering role on the development of infrared spectroscopic imaging. His work has included the development of novel theory and modeling of infrared imaging and its use for spectral analysis, the development of instrumentation and of computational methods to extract high-fidelity information to enable challenging studies to be conducted. His work has focused on the applications of spectroscopic imaging to biomedical sciences, especially on cancer biology and clinical applications by research case studies. Instruments developed in his laboratory have been used to provide new means to characterize and define cancer using chemical imaging. (press release)

            Dr. Scott W. Lowe

            Dr. Scott W. Lowe
            Chair, Cancer Biology & Genetics Program, Sloan Kettering Institute
            Chair, Geoffrey Beene Cancer Research Center
            Memorial Sloan Kettering Cancer Center
            New York, NY

            Awarded in August 2016

            Dr. Lowe studies have contributed to the understanding of several important tumor suppressor genes, including p53, APC and PTEN. Likewise, he has built numerous genetic screens and animal models that have played important roles in the identification and characterization of new drug targets, as well as in identifying vulnerabilities of cancer cells that might be susceptible to new therapies. Some of these screens and animal models have made extensive use of shRNAi libraries. More recently, Dr. Lowe has adopted the CRISPR/Cas 9 to further exploit the benefits of this technology to advance our understanding and management of cancer. (press release)

            Dr. Peter Robinson

            Dr. Peter Robinson
            Professor of Computational Biology
            The Jackson Laboratory for Genomic Medicine
            Farmington, CT

            Awarded in February 2016

            Dr. Robinson is well known for the development of the Human Phenotype Ontology, a standardized vocabulary of phenotypic abnormalities encountered in human disease, and he has created methods to identify a number of novel disease genes. Dr. Robinson studied mathematics and computer science at Columbia University and medicine at the University of Pennsylvania. He completed training as a pediatrician at the Free University of Berlin and Charité University Hospital. (press release)

            Dr. Shilin Chen

            Dr. Shilin Chen 
            Director, Institute of Chinese Materia Medica,
            China Academy of Chinese Medical Sciences
            Beijing, China

            Awarded in February 2016

            Dr. Chen is the Director of the Institute of Chinese Materia Medica at the China Academy of Chinese Medical Sciences in Beijing. His work on the field of medicinal chemistry of natural products, associated with the determination of the active ingredient of traditional Chinese medicines and the identification of their mechanism of action, is well recognized. This includes but is not limited to the family of antimalarial drugs such as artemisinin. Likewise, Dr. Chen has pioneered the use of genomic approaches, such as NGS sequencing and DNA barcoding for identification of medicinal plant species. (press release)

            Dr. Jeffrey I. Gordon

            Dr. Jeffrey I. Gordon 
            The Dr. Robert J. Glaser Distinguished University Professor and
            Director of the Center for Genome Sciences & Systems Biology
            Washington University School of Medicine
            St. Louis, MO

            Awarded in October 2015

            Dr. Gordon is recognized internationally as a pioneer and leader of the Microbiome research field. His efforts, including the influential 2005 NHGRI white-paper entitled "Extending Our View of  Self: the Human Gut Microbiome Initiative (HGMI)" lead to the creation of the NIH "Human Microbiome Project Roadmap for Medical Research" funding initiative in 2007. Dr. Gordon's research is focused on understanding the mutualistic interactions that occur between humans and the trillions of commensal microbes that colonize each person’s gastrointestinal tract. His research employs germ-free mice as model hosts as well as metagenomics, metabolomics, microbiology, biochemistry and nutritional sciences to study the composition of the human gut microbiome and their roles and  consequences for human health and development. Of particular interest to him and his group are areas related to malnutrition, obesity as well as to neuro and  immune modulation and development. (press release)

            Dr. Lawrence J. Lesko

            Dr. Lawrence J. Lesko 
            Department of Pharmaceutics
            College of Pharmacy
            University of Florida,
            Orlando, Florida

            Awarded in March 2015

            Dr. Lesko directs the Center for Pharmacometrics and Systems Pharmacology at University of Florida’s College of Pharmacy in Lake Nona. Before joining UF, Dr. Lesko worked nearly 20 years in the FDA’s Center for Drug Evaluation and Research as the Director of the Office of Clinical Pharmacology.  He was also Chair of the Clinical Pharmacology Coordinating Subcommittee of the FDA’s Medical Policy Coordinating Committee and authored or co-authored numerous Guidance for Industry, and started the FDA’s Voluntary Genomics Data Submission Program and Mechanistic Drug Safety Program. (press release)

            Dr. Arturo A. Keller

            Dr. Arturo A. Keller
            Department of Environmental Biogeochemistry
            Bren School
            University of California, Santa Barbara
            Santa Barbara, CA

            Awarded March 2015

            Dr. Arturo Keller directs the Center for the Environmental Implications of Nanotechnology at UCSB. He has earned international recognition for his research into the uptake, accumulation and biotransformation of nanoparticles in natural waters and soil. A particular interest of his research is focused on the analysis of nanoparticles for its safe and sustainable introduction by the agro industry. (press release)

            Dr. Jules Griffin

            Dr. Jules Griffin
            Department of Biochemistry
            University of Cambridge
            United Kingdom

            Awarded: September 2014

            Dr. Jules Griffin is an Honorary Professor at Imperial College London, a Fellow of King's College and  Senior Lecturer in the Department of Biochemistry at the University of Cambridge. He also heads the MRC Lipid Profiling and Signalling program. His work focusses on the use of high resolution mass spectrometry to measure lipids in biofluids and tissue extracts in order to better understand the causes and consequences of type 2 diabetes and obesity (collectively referred to sometimes as the Metabolic Syndrome) and developing computer software tools for storing and processing the large quantity of data produced by these experiments. (press release)

            Dr. Cordon-Cardo

            Dr. Carlos Cordon-Cardo
            The Irene Heinz Given and John LaPorte Given Professor
            and Chair of Pathology for the Mount Sinai Health System
            Dept. of Pathology
            The Mount Sinai Hospital
            New York, NY

            Awarded: August 2014

            Dr. Cordon-Cardo is a distinguished clinician and researcher recognized internationally for his groundbreaking research in experimental pathology and molecular oncology. His research has focused on the analyses of multidrug resistance, alteration of tumor suppression genes in human cancer and on the isolation and characterization of human cancer stem cells. He has also contributed to the development and implementation of the oncology molecular pathology discipline and helped create the "systems pathology platform. (press release)

            Dr. Carolyn Mountford

            Dr. Carolyn Mountford
            Centre for MR in Health
            School of Health Sciences
            Faculty of Health and Medicine
            University of Newcastle
            Australia

            Awarded: April 2013

            Dr. Mountford is a professor of radiology at The University of Newcastle Australia School of Health Sciences, and Harvard Medical School. She is the director of Newcastle's Magnetic Resonance Centre for Clinical Research and director of the Center for Clinical Spectroscopy at the Brigham and Women's Hospital in Boston. Dr. Mountford is known for her innovative work using nuclear magnetic resonance (NMR) spectroscopy technology in cancer research. (press release)

            Dr. John Rabinowitz

            Dr. John A. McLean
            Stevenson Professor
            Department of Chemistry
            Vanderbilt University
            Nashville, TN

            Awarded: March 2014

            In Vanderbilt's Department of Chemistry, Prof. McLean and colleagues focus on the conceptualization, design, and construction of structural mass spectrometers, specifically targeting complex samples in systems, synthetic, and chemical biology as well as nanotechnology. His group applies these strategies to forefront translational research areas in drug discovery, personalized medicine, and 'human-on-chip' synthetic biology platforms. (press release)

            Dr. Joshua D. Rabinowitz

            Dr. Joshua D. Rabinowitz
            Professor of Chemistry and Integrative Genomics
            Princeton University
            Princeton, NJ

            Awarded: October 2013

            Dr. Rabinowitz has made seminal conceptual and methodological contributions to the metabolomics field. These include the development of isotopic labeling, sample preparation, data analysis, and information visualization techniques for liquid chromatography/mass spectrometry data. (press release)

            Dr. Paul B. Watkins

            Dr. Paul B. Watkins
            Professor of Medicine, Toxicology, and Experimental Therapeutics
            Director, Institute for Drug Safety Sciences
            The Hamner Institutes for Health Sciences
            Research Triangle Park, NC

            Awarded: October 2013

            Paul B. Watkins, M.D., is the Professor of Medicine, Professor of Toxicology, and Professor of Experimental Therapeutics at The University of North Carolina at Chapel Hill (UNC), and serves as Director of the Institute for Drug Safety Sciences. As an internationally recognized expert in drug safety, Dr. Watkins has extensive research experience in drug-induced liver injury (DILI), which includes basic investigation in drug metabolism and transport, clinical studies, causation assessment, and regulatory affairs. (press release)

            Dr. Junying Yuan

            Dr. Junying Yuan
            Director of the Interdisciplinary Research Center on Biology
            Chinese Academy of Science
            Shanghai, China

            Awarded: November 2013

            Dr. Junying Yuan is a pioneer and leading researcher in the field of cell death. The Agilent Thought Leader award will support metabolomics and integrated biology efforts for the identification of neurodegenerative diseases biomarkers at the Chinese Academy of Science's newly established Interdisciplinary Research Center on Biology and Chemistry. (press release)

            Dr. Guibin Jiang

            Dr. Guibin Jiang
            Director of State Key Laboratory of Environmental Chemistry and Ecotoxicology
            Chinese Academy of Sciences
            Haidian District,
            Beijing, China

            Awarded: October 2013

            Dr. Jiang's research is mainly focused on analytical chemistry and environmental chemistry. His methodical and comprehensive research has resulted in significant achievements on analytical development and environmental characterization of persistent organic pollutants (POPs), and the speciation of organometallic compounds, which have contributed to the improvement and internationalization of these scientific fields in China. (press release)

            Dr. Emmanuel Barillot

            Dr. Emmanuel Barillot
            Director of Bioinformatics and Systems IT
            Institut Curie
            Paris, France

            Awarded: August 2013

            Dr. Barillot's area of work is in the development of a database of cellular signaling pathways and a visualization tool to help the pharmaceutical industry develop more effective cancer treatments. (press release)

            Dr. Hashim Al-Hashimi

            Dr. Hashim Al-Hashimi
            J. Lawrence Oncley Collegiate Professor of Chemistry and Biophysics
            Dept. of Chemistry and Biophysics
            University of Michigan
            Ann Arbor, MI

            Awarded: March 2013

            Dr. Hashim Al-Hashimi is an influential researcher in the realm of structural biology. Dr. Al-Hashimi and his team at the University of Michigan are developing advanced methods to characterize Hoogsteen base pairs — a rare form of DNA that is structurally distinct from the typical double helix — using nuclear magnetic resonance spectroscopy. Hoogsteen base pairs, named after biochemist Karst Hoogsteen, are of particular interest because of their unusual structure and biological functions. Dr. Al-Hashimi and his team believe their research could lead to significant advances in DNA-targeted drug discovery and other applications. (press release)

            Dr. Ronald DePinho

            Dr. Ronald DePinho
            President, MD Anderson Cancer Center
            University of Texas
            Houston, TX

            Awarded: December 2012

            Dr. Ronald A. DePinho, a world-renowned oncologist and researcher, has received an Agilent Thought Leader Award in support of his research into metabolic reprogramming in the earliest stages of cancer. He is internationally recognized for basic and translational research in cancer, aging and age-associated degenerative disorders. He is only the fourth full-time president in the 70-year history of MD Anderson. (press release)

            Dr. Robert E. Gerszten

            Dr. Robert Gerszten
            Director of Clinical and Translational Research
            Institute for Heart, Vascular and Stroke Care
            Massachusetts General Hospital
            Boston, MA

            Awarded: November 2012

            Dr. Robert E. Gerszten received an Agilent Thought Leader award in support of his research on the discovery of metabolite biomarkers for cardiovascular and related metabolic diseases. Dr Gerszten has pioneered the use of proteomics and metabolomics approaches to identify biomarkers of these diseases using the Framingham heart study cohort. (press release)

            Dr. Jens Frisvad

            Dr. Jens Frisvad
            Professor, Department of Systems Biology
            Center for Microbial Biotechnology
            Technical University of Denmark
            Lyngby, Denmark

            Awarded: May 2012

            Prof. Frisvad's research is primarily in the area of fungi. His work focuses on the biochemical diversity in molds with a view to finding new enzymes and secondary metabolites which can be used in new drugs. In addition, he works on projects involving the study of mycotoxins and molds from Penicillium and Aspergillus, in an effort to prevent toxin-formation in food, indoor climates, and biotechnological products. (press release)

            Dr. Russell Thomas

            Dr. Russell Thomas
            Senior Investigator
            Director, Institute for Chemical Safety Sciences
            Director, Center for Genomic Biology and Bioinformatics
            Hamner Institutes for Health Sciences

            Awarded: December 2011

            Russell S. Thomas, Ph.D., of the Hamner Institutes for Health Sciences has been selected for an Agilent Thought Leader Award to support his work developing methods to predict drug-induced liver injury. The award includes funding from the Agilent Technologies Foundation as well as instrumentation from the company, including a 6460 triple quadrupole LC/MS and an Agilent microarray scanner. Dr. Thomas is director of the Institute for Chemical Safety Sciences at the Hamner, where researchers are applying a systems biology approach in an effort to predict drug-induced liver injury. (press release)

            Dr. Chris Evelo

            Dr. Chris Evelo
            Department Head, Bioinformatics BiGCaT
            Maastricht University
            Maastricht, Netherlands

            Awarded: November 2011

            Dr. Chris Evelo at the department of bioinformatics at Maastricht University is the recipient of an Agilent Thought Leader Award supporting development of software to integrate different types of biological data. The goal of this award is to help accelerate breakthroughs in disease research by facilitating integrative systems biology approaches. The Evelo Lab helped develop WikiPathways.org as a community-curated platform for structuring multi-omics data and the associated open-access pathway analysis tool PathVisio. (press release)

            Dr. Steven Carr

            Dr. Steven Carr
            Senior Scientific Leader, Protein Biochemistry and Proteomics
            Broad Institute
            Cambridge, MA

            Awarded: October 2011

            Dr. Steven Carr of the Broad Institute (affiliated with the Massachusetts Institute of Technology and Harvard University) has been selected for an Agilent Thought Leader Award. The award will support Carrs efforts to develop new technologies for analyzing proteins and peptides, intended to help doctors diagnose illnesses such as cardiovascular disease, breast cancer and ovarian cancer. (press release)

            Prof. Gerhard Wagner

            Dr. Gerhard Wagner
            Department of Biological Chemistry and Molecular Pharmacology
            Harvard Medical School
            Boston, MA

            Awarded: August 2011

            Dr. Gerhard Wagner of the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School received an Agilent Thought Leader award in support of his effort to develop methods for studying biologically relevant systems that pose a serious challenge for modern structural biology tools. Prof. Wagner's work will greatly enhance the impact of NMR spectroscopy for large protein assignment and structure determination by matching the capabilities of modern high-field instruments with suitable acquisition and processing methods. (press release)

            Dr. Adam Arkin

            Dr. Adam Arkin
            Director, Synthetic Biology Institute
            Dean A. Richard Newton Memorial Professor,
            Department of Bioengineering
            University of California, Berkeley
            Director, Physical Biosciences Division, Lawrence Berkeley National Lab

            Awarded: April 2011

            Adam Arkin, director of SBI and of the Physical Biosciences Division at LBNL, is the Dean A. Richard Newton Memorial Professor in UC Berkeleys Department of Bioengineering. He is also co-director of the Virtual Institute of Microbial Stress and Survival, director of bioinformatics at the Joint Bioenergy Institute, and co-director of BIOFAB (International Open Facility Advancing Biotechnology). His research centers on uncovering the evolutionary design principles of cellular networks and populations and exploiting them for applications. He and colleagues are developing a framework to facilitate applications in health, the environment, and bioenergy by combining comparative functional genomics, quantitative measurement of cellular dynamics, biophysical modeling of cellular networks, and cellular circuit design. (press release)

            Dr. Bart Weimer

            Dr. Bart Weimer
            Professor, Population Health & Reproduction
            School of Veterinary Medicine
            University of California, Davis

            Awarded: January 2011

            Dr. Weimer's laboratory group at the School of Veterinary Medicine focuses on microbial physiology and function. Research on host/microbe interactions has led to the elucidation of the competitive binding of beneficial bacteria to the gut epithelium and the resulting displacement of pathogenic bacteria such as salmonella. Using genomics and functional genomics gene expression, metabolomics, proteomics, and metagenomics Dr. Weimer's program examines the mechanisms of gene interplay to produce a specific phenotype and the metabolism involved in the process.

            Dr. David Botstein

            Dr. David Botstein
            Lewis-Sigler Institute for Integrative Genomics
            Princeton University

            Awarded: November 2010

            Dr. David Botstein, professor and director of the Lewis-Sigler Institute for Integrative Genomics and the Center for Quantitative Biology at Princeton University, received an Agilent Thought Leader award in support of his research in the area of genomics. This award of cash funding and Agilent products to the Lewis-Sigler Institute for Integrative Genomics will allow Dr. Botstein to produce the most complete genomic, proteomic and metabolomic data sets from any eukaryote (organism with cells containing membrane-enclosed structures including nucleus) to date. (press release)

            Dr. Hailu Kinde

            Dr. Hailu Kinde
            UC Davis School of Veterinary Medicine California Animal Health and Food Safety Laboratory

            Awarded: October 2010

            Dr. Hailu Kinde, professor at the California Animal Health and Food Safety Laboratory System, received an Agilent Thought Leader award in support of his research in the area of food safety. This award of cash funding and Agilent products to the UC Davis School of Veterinary Medicine will allow Dr. Kinde to focus on the development of a new process that can reduce the time required to identify food-borne pathogens from several days to only a few hours. (press release)

            Dr. Thomas Hartung

            Dr. Thomas Hartung
            Director for the Center for Alternatives to Animal Testing (CAAT)
            Bloomberg School of Public Health
            Johns Hopkins University

            Awarded: August 2010

            Dr. Thomas Hartung received an Agilent Thought Leader award in support of his research on for the use of toxicity pathways to predict developmental neurotoxicity. Through this award of funding from the Agilent Foundation and a company donation of instruments to the Center for Alternatives to Animal Testing (CAAT) at the Johns Hopkins Bloomberg School of Public Health, Dr. Hartung will focus his research on the identification of novel toxicity pathways by combining two promising cell culture models with emerging metabolomics. This work could help identify possible contributions of chemicals to disorders such as autism and attention hyperactivity disorders. (press release)

            Dr. James J. Collins

            Dr. James Collins
            Professor of Biomedical Engineering
            Wyss Institute for Biologically Inspired Engineering

            Awarded: July 2010

            Dr. James Collins is developing innovative ways to reprogram organisms, particularly bacteria, to perform desired tasks, such as attacking tumors and guiding development of stem cells. These programmed bacteria could lead to cheaper drugs, greener fuels, and more effective treatments for antibiotic-resistant infections and diseases. He is a pioneer in systems biology, stochastic resonance, biological dynamics, and neurostimulation, with the goal of improving the function of physiological and biological systems. (press release)

            Dr. George Church

            Dr. George Church
            Professor of Genetics
            Harvard Medical School
            Director of the Center for Computational Genetics
            Wyss Institute for Biologically Inspired Engineering
            Boston, MA

            Awarded: July 2010

            Dr. George Church is Professor of Genetics at Harvard Medical School and Director of NIH-CEGS and DOE-GTL Genomics Centers. He has pioneered technology innovations early in the development of key fields in chemistry and biomedicine with 10 US Patents granted and several pending. As part of technology transfer to the commercial sector he has served on 22 scientific advisory boards. In 1976, his crystallographic software lead to the first high-resolution folded-RNA structure (a decade before similar structures important for ribozymes, aptamers, and RNAi). (press release)

            Dr. Don Ingber

            Dr. Don Ingber
            Wyss Institute Founding Director
            and Core Faculty Member
            Platform Leader, Biomimetic Microsystems

            Awarded: July 2010

            Dr. Ingber is Founding Director of the Wyss Institute and a leader in the emerging field of biologically inspired engineering. He oversees a multifaceted effort to identify the mechanisms that living organisms use to self assemble and to apply these design principles to develop advanced materials and devices. Dr. Ingber was the first researcher to recognize that tensegrity architecture (in which a system stabilizes itself mechanically by balancing local compression with continuous tension) is a fundamental principle in the way living organisms are structured at the nanometer scale. (press release)

            Dr. Janne Lehti

            Dr. Janne Lehtio
            Karolinska Institute
            Department of Oncology-Pathology
            Science for Life Laboratory

            Awarded: June 2010

            Dr. Janne Lehtio has worked on clinical proteomics both in academia and biotech industry. In 2004, Dr. Lehtio was selected to build mass spectrometry based proteomics at Karolinska University Hospital and continues his proteomics research there. Today, Dr. Lehtio leads a mass-spectrometry-based proteomics group at Karolinska Institutet focusing on quantitative proteomics methods development and cancer proteomics. In recent year his lab has developed several methods for clinical proteomics and currently uses these methods to understand proteome changes related to cancer therapy.

            Dr. Pauline Rudd

            Dr. Pauline Rudd
            Professor of Glycobiology
            University College Dublin
            National Institute for Bioprocessing Research and Training (NIBRT)

            Awarded: May 2010

            Dr. Pauline Rudd received an Agilent Thought Leader award in March 2010 in support of emerging glycomics research through a grant of funding and instruments to the National Institute for Bioprocessing Research and Training (NIBRT) at the University College Dublin in Ireland. The goal of the research is to develop novel approaches to analyze protein glycosylation as part of the characterization process of recombinant protein drugs and to study disease glycan biomarkers using liquid chromatography mass spectrometry. (press release)

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